Substitution and Elimination Reactions

Substitution and Elimination Reactions

This webinar addresses the major reaction types tested on the MCAT. You will learn about the different types of substitution and elimination reactions, their mechanisms, and how to predict the mechanism of a given reaction based on the reaction conditions. You will also learn how to determine the correct product of a substitution or elimination reaction.

At a glance


Essential skills

  • Follow reaction mechanisms

  • Predict products and mechanisms given reaction conditions

  • Determine stereochemistry inversion or scrambling

  • Apply your prior knowledge of nomenclature and chemical kinetics!


Knowledge Fundamentals

  • Orgo basics (behaviors and arrow pushing)

  • Substitution vs. elimination

  • SN1 vs. SN2

  • E1 vs. E2

  • Conditions that favor each type of reaction

  • Stereochemistry considerations of substitution reactions


On the MCAT

  • The test heavily favors substitution reactions over elimination reactions, yet has been known to test elimination reactions in basic ways like how they are similar to their substitution counterparts.

  • Questions will often give reaction conditions that will favor one mechanism over the other


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